Evidence-based health education

First the evidence.Then the claim.

I'm Dr. Holger Scheib, a chemist. I trace ingredients and studies back to the source and tell you what's backed by evidence and what just sounds good.

No spam. Substance only. Unsubscribe anytime.

How I work

Dr. Holger Scheib

Chemist · The HealthChemist

Own research, published in

NaturePNASJ. Med. Chem.

Peer-reviewed work at the intersection of chemistry, biology and nutrition.

At a glance

The HealthChemist explains health and ingredient topics based on real studies. Every claim is visibly labelled: proven, plausible or hypothesis. No wonder cures, no fear-mongering.

The finding

“Green tea slows sugar absorption.”

Hypothesis

A mechanism is conceivable. Nothing more, yet.

Plausible

In the lab, flavonoids inhibit α-amylase, the enzyme that splits starch. Meta-analyses show a real but tiny effect on fasting blood glucose in humans.

Proven

Nothing stands here. The long-term marker HbA1c does not move.

And here it stays. The mechanism is clean, the effect in humans measurable — and so small that it decides nothing in everyday life. I co-authored the underlying paper myself. That is precisely why I do not say “proven”.

Lo Piparo, Scheib et al., J. Med. Chem. 2008 (PMID 18507367) · Zheng et al., Am. J. Clin. Nutr. 2013 (PMID 23426037) · Xu et al., Nutr. Metab. 2020 (PMID 32670385)

My promise

Three levels. Clearly separated.

Online, the line between what is proven and what is merely claimed blurs all the time. That is why every claim I make gets a quality label, like a traffic light.

Proven

Backed by robust studies. The source is named, and I describe the evidence honestly, limits included.

Plausible

Mechanistically reasonable or supported by early data, but not yet firmly proven. Named for exactly what it is.

Hypothesis

A reasoned guess. Interesting, but open. I flag it rather than selling it as certainty.

Why a chemist

Without chemistry, there is no life.

Many people talk about healthy products, and hardly anyone understands what is actually in them. So I read the ingredient list as what it chemically is. A list of molecules, each of which can be checked.

My background is computational chemistry and structural biology. For years I studied how small molecules act in the body. I now use that toolkit to make studies readable for you.

More about my background
Dr Holger Scheib studies the structure of the human sodium channel Nav1.2 (PDB 6J8E) on screen.

Topics

What I write about

My focus is ingredients and nutrition. Where my own research exists, I point to it; everything else I back with external sources and say so.

Dr Holger Scheib in a supermarket aisle, checking the nutrition and ingredient panel on the back of a package.

Understanding ingredients

What is behind the name on the label? I look at effect, dose and the state of the evidence, not at the promise printed next to it.

Nutrition & nutrients

What polyphenols, vitamins and the rest actually do in the body, and where the data gets thin.

Myth versus evidence

Popular health claims, calmly examined. The study is real; the real question is often the conclusion drawn from it.

Articles

Read along. Think along.

New articles appear regularly, and every one carries the traffic light. Join me in this quest.

Go to the articles

Newsletter

Shall I send you the next article?

I write irregularly but thoroughly: new articles, honestly sorted into proven, plausible and hypothesis. No spam, no sales funnel.

No spam. Substance only. Unsubscribe anytime.

Contact

Do you have a question or topic idea?

Send me a short note about what you have in mind. Questions, topic ideas and collaboration enquiries all land here. I'm not trying to sell you anything along the way.